Dysregulated Myosin in HPS lung fibroblasts

Jul 27, 2022

Subject: Dysregulated myosin in Hermansky-Pudlak syndrome lung fibroblasts is associated with increased cell motility – PubMed

Researchers continue to study pulmonary fibrosis in the HPS population.  Myosin is a protein that has a role in muscle contraction. Increased levels are found in pulmonary fibrosis of HPS1. In vivo (using Zebrafish), Losartan (drug used to lower blood pressure) decreases Myosin and movement of HPS lung fibroblasts which contributes to the development of pulmonary fibrosis. This research has immeasurable value to our community.

Flavia's Journal Club